128 citations · 365 across the 9 of their papers we have counts for
10 papers
The functional impact of myofiber macroscopic organization and disarray in computational models of the murine heart
Carlo Guastamacchia, Roberto Piersanti, Francesco Giardini +5
A major challenge in computational models of cardiac electromechanics is the reconstruction of myocardial fiber architecture, as direct in vivo measurements of fiber orientation ar…
Coupled Eikonal problems to model cardiac reentries in Purkinje network and myocardium
Samuele Brunati, Michele Bucelli, Roberto Piersanti +2
We propose a novel partitioned scheme based on Eikonal equations to model the coupled propagation of the electrical signal in the His-Purkinje system and in the myocardium for card…
Defining myocardial fiber bundle architecture in atrial digital twins
Roberto Piersanti, Ryan Bradley, Syed Yusuf Alid +3
A key component in developing atrial digital twins (ADT) - virtual representations of patients' atria - is the accurate prescription of myocardial fibers which are essential for th…
An integrated heart-torso electromechanical model for the simulation of electrophysiogical outputs accounting for myocardial deformation
Elena Zappon, Matteo Salvador, Roberto Piersanti +3
When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on singl…
lifex-ep: a robust and efficient software for cardiac electrophysiology simulations
Pasquale C. Africa, Roberto Piersanti, Francesco Regazzoni +6
Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the need for streamlined, accurate, and high-…
An electromechanics-driven fluid dynamics model for the simulation of the whole human heart
Alberto Zingaro, Michele Bucelli, Roberto Piersanti +3
We introduce a multiphysics and geometric multiscale computational model, suitable to describe the hemodynamics of the whole human heart, driven by a four-chamber electromechanical…
A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
Marco Fedele, Roberto Piersanti, Francesco Regazzoni +6
While ventricular electromechanics is extensively studied, four-chamber heart models have only been addressed recently; most of these works however neglect atrial contraction. Inde…
An open tool based on lifex for myofibers generation in cardiac computational models
Pasquale C. Africa, Roberto Piersanti, Marco Fedele +2
Modeling the whole cardiac function involves the solution of several complex multi-physics and multi-scale models that are highly computationally demanding, which call for simpler…
3D-0D closed-loop model for the simulation of cardiac biventricular electromechanics
Roberto Piersanti, Francesco Regazzoni, Matteo Salvador +4
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which are also essential to reproduce the synchronous activity of the heart, are: i) accounting…
Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations
Roberto Piersanti, Pasquale C. Africa, Marco Fedele +4
Since myocardial fibers drive the electric signal propagation throughout the myocardium, accurately modeling their arrangement is essential for simulating heart electrophysiology (…