21 citations · 104 across the 23 of their papers we have counts for
23 papers
Robust Instability Radius for Networked Dynamical Systems: Upper and Lower Bounds
Shinji Hara, Yutaka Hori, Tetsuya Iwasaki +2
This paper is concerned with robust instability of uncertain network systems. We consider the multi-agent system described as a network of single-input-single-output agents with id…
Exact Robust Instability Analysis for Networked Dynamical Systems with Biological Application
Shinji Hara, Yutaka Hori, Tetsuya Iwasaki +2
This paper investigates robust instability in nominally unstable uncertain networked dynamical systems, where all nominal agents share an identical single-input-single-output (SISO…
Bounding Transient Moments for a Class of Stochastic Reaction Networks Using Kolmogorov's Backward Equation
Takeyuki Iwasaki, Yutaka Hori
Stochastic chemical reaction networks (SRNs) in cellular systems are commonly modeled as continuous-time Markov chains (CTMCs) describing the dynamics of molecular copy numbers. Th…
Acceleration of Moment Bound Optimization for Stochastic Chemical Reactions Using Reaction-wise Sparsity of Moment Equations
Tomoki Sadatoshi, Antonis Papachristodoulou, Yutaka Hori
Moment dynamics in stochastic chemical kinetics often involve an infinite chain of coupled equations, where lower-order moments depend on higher-order ones, making them analyticall…
Stability analysis for circulant structured multi-agent molecular communication systems
Taishi Kotsuka, Yutaka Hori
In this paper, we introduce the system theoretic model for the multi-agent MC systems represented by multi-input and multi-output (MIMO) systems using the transfer functions, and t…
On Phase Change Rate Maximization with Practical Applications
Chung-Yao Kao, Shinji Hara, Yutaka Hori +2
We recapitulate the notion of phase change rate maximization and demonstrate the usefulness of its solution on analyzing the robust instability of a cyclic network of multi-agent s…
A Control-theoretic Model for Bidirectional Molecular Communication Systems
Taishi Kotsuka, Yutaka Hori
Molecular communication (MC) enables cooperation of spatially dispersed molecular robots through the feedback control mediated by diffusing signal molecules. However, conventional…
Frequency response of diffusion-based molecular communication channels in bounded environment
Taishi Kotsuka, Yutaka Hori
Recently, molecular communication (MC) has been studied as a micro-scale communication between cells or molecular robots. In previous works, the MC channels in unbounded environmen…
Exact Instability Margin Analysis and Minimum-Norm Strong Stabilization -- phase change rate maximization --
Shinji Hara, Chung-Yao Kao, Sei Zhen Khong +2
This paper is concerned with a new optimization problem named "phase change rate maximization" for single-input-single-output linear time-invariant systems. The problem relates to…
Interval Analysis of Worst-case Stationary Moments for Stochastic Chemical Reactions with Uncertain Parameters
Yuta Sakurai, Yutaka Hori
The dynamics of cellular chemical reactions are variable due to stochastic noise from intrinsic and extrinsic sources. The intrinsic noise is the intracellular fluctuations of mole…
Robust Instability Radius for Multi-agent Dynamical Systems with Cyclic Structure
Shinji Hara, Tetsuya Iwasaki, Yutaka Hori
This paper is concerned with robust instability analysis for linear multi-agent dynamical systems with cyclic structure. This relates to interesting and important periodic oscillat…
Instability Margin Analysis for Parametrized LTI Systems with Application to Repressilator
Shinji Hara, Tetsuya Iwasaki, Yutaka Hori
This paper is concerned with a robust instability analysis for the single-input-single-output unstable linear time-invariant (LTI) system under dynamic perturbations. The nominal s…
Robust Instability Analysis with Application to Neuronal Dynamics
Shinji Hara, Tetsuya Iwasaki, Yutaka Hori
This paper is concerned with robust instability analysis of linear feedback systems subject to a dynamic uncertainty. The work is motivated by, and provides a basic foundation for,…
Analyzing Diffusion and Flow-driven Instability using Semidefinite Programming
Yutaka Hori, Hiroki Miyazako
Diffusion and flow-driven instability, or transport-driven instability, is one of the central mechanisms to generate inhomogeneous gradient of concentrations in spatially distribut…
Bounding Transient Moments of Stochastic Chemical Reactions
Yuta Sakurai, Yutaka Hori
The predictive ability of stochastic chemical reactions is currently limited by the lack of closed form solutions to the governing chemical master equation. To overcome this limita…
A Convex Approach to Steady State Moment Analysis for Stochastic Chemical Reactions
Yuta Sakurai, Yutaka Hori
Model-based prediction of stochastic noise in biomolecular reactions often resorts to approximation with unknown precision. As a result, unexpected stochastic fluctuation causes a…
Coordinated Spatial Pattern Formation in Biomolecular Communication Networks
Yutaka Hori, Hiroki Miyazako, Soichiro Kumagai +1
This paper proposes a control theoretic framework to model and analyze the self-organized pattern formation of molecular concentrations in biomolecular communication networks, emer…
Collective oscillation period of inter-coupled biological negative cyclic feedback oscillators
Yongqiang Wang, Yutaka Hori, Shinji Hara +1
A number of biological rhythms originate from networks comprised of multiple cellular oscillators. But analytical results are still lacking on the collective oscillation period of…
Turing Instability in Reaction-Diffusion Systems with a Single Diffuser: Characterization Based on Root Locus
Hiroki Miyazako, Yutaka Hori, Shinji Hara
Cooperative behaviors arising from bacterial cell-to-cell communication can be modeled by reaction-diffusion equations having only a single diffusible component. This paper present…
Noise-Induced Spatial Pattern Formation in Stochastic Reaction-Diffusion Systems
Yutaka Hori, Shinji Hara
This paper is concerned with stochastic reaction-diffusion kinetics governed by the reaction-diffusion master equation. Specifically, the primary goal of this paper is to provide a…
Existence of Oscillations in Cyclic Gene Regulatory Networks with Time Delay
Masaaki Takada, Yutaka Hori, Shinji Hara
This paper is concerned with conditions for the existence of oscillations in gene regulatory networks with negative cyclic feedback, where time delays in transcription, translation…
Biochemical Oscillations in Delayed Negative Cyclic Feedback: Harmonic Balance Analysis with Applications
Yutaka Hori, Shinji Hara
Oscillatory chemical reactions often serve as a timing clock of cellular processes in living cells. The temporal dynamics of protein concentration levels is thus of great interest…
The collective oscillation period of inter-coupled Goodwin oscillators
Yongqiang Wang, Yutaka Hori, Shinji Hara +1
Many biological oscillators are arranged in networks composed of many inter-coupled cellular oscillators. However, results are still lacking on the collective oscillation period of…