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q-bio.GN2023
Statistical Power Analysis for Designing Bulk, Single-Cell, and Spatial Transcriptomics Experiments: Review, Tutorial, and Perspectives
Hyeongseon Jeon, Juan Xie, Yeseul Jeon +4
Gene expression profiling technologies have been used in various applications such as cancer biology. The development of gene expression profiling has expanded the scope of target…
q-bio.GN2022
graph-GPA 2.0: A Graphical Model for Multi-disease Analysis of GWAS Results with Integration of Functional Annotation Data
Qiaolan Deng, Jin Hyun Nam, Ayse Selen Yilmaz +5
Genome-wide association studies (GWAS) have successfully identified a large number of genetic variants associated with traits and diseases. However, it still remains challenging to…