152 citations · 472 across the 20 of their papers we have counts for
20 papers
Limitations of Rotational Acceleration for Predicting Concussion: A New Injury Risk Function
Jessica A. Towns, Nicholas J. Cecchi, James W. Hickey +9
Purpose: Rotational acceleration of the head has long been hypothesized to be a primary driver of concussion because it can generate shear strains in brain tissue, whereas linear a…
Differences between Two Maximal Principal Strain Rate Calculation Schemes in Traumatic Brain Analysis with in-vivo and in-silico Datasets
Xianghao Zhan, Zhou Zhou, Yuzhe Liu +5
Brain deformation caused by a head impact leads to traumatic brain injury (TBI). The maximum principal strain (MPS) was used to measure the extent of brain deformation and predict…
Identification of head impact locations, speeds, and force based on head kinematics
Xianghao Zhan, Yuzhe Liu, Nicholas J. Cecchi +5
Objective: Head impact information including impact directions, speeds and force are important to study traumatic brain injury, design and evaluate protective gears. This study pre…
Linking Symptom Inventories using Semantic Textual Similarity
Eamonn Kennedy, Shashank Vadlamani, Hannah M Lindsey +79
An extensive library of symptom inventories has been developed over time to measure clinical symptoms, but this variety has led to several long standing issues. Most notably, resul…
Toward more accurate and generalizable brain deformation estimators for traumatic brain injury detection with unsupervised domain adaptation
Xianghao Zhan, Jiawei Sun, Yuzhe Liu +5
Machine learning head models (MLHMs) are developed to estimate brain deformation for early detection of traumatic brain injury (TBI). However, the overfitting to simulated impacts…
Denoising instrumented mouthguard measurements of head impact kinematics with a convolutional neural network
Xianghao Zhan, Yuzhe Liu, Nicholas J. Cecchi +6
Wearable sensors for measuring head kinematics can be noisy due to imperfect interfaces with the body. Mouthguards are used to measure head kinematics during impacts in traumatic b…
Padded Helmet Shell Covers in American Football: A Comprehensive Laboratory Evaluation with Preliminary On-Field Findings
Nicholas J. Cecchi, Ashlyn A. Callan, Landon P. Watson +8
Protective headgear effects measured in the laboratory may not always translate to the field. In this study, we evaluated the impact attenuation capabilities of a commercially avai…
Data-driven decomposition of brain dynamics with principal component analysis in different types of head impacts
Xianghao Zhan, Yuzhe Liu, Nicholas J. Cecchi +4
Strain and strain rate are effective traumatic brain injury predictors. Kinematics-based models estimating these metrics suffer from significant different distributions of both kin…
Rapidly and accurately estimating brain strain and strain rate across head impact types with transfer learning and data fusion
Xianghao Zhan, Yuzhe Liu, Nicholas J. Cecchi +4
Brain strain and strain rate are effective in predicting traumatic brain injury (TBI) caused by head impacts. However, state-of-the-art finite element modeling (FEM) demands consid…
Physics-informed machine learning improves detection of head impacts
Samuel J. Raymond, Nicholas J. Cecchi, Hossein Vahid Alizadeh +6
In this work we present a new physics-informed machine learning model that can be used to analyze kinematic data from an instrumented mouthguard and detect impacts to the head. Mon…
Kinematics clustering enables head impact subtyping for better traumatic brain injury prediction
Xianghao Zhan, Yiheng Li, Yuzhe Liu +5
Traumatic brain injury can be caused by various types of head impacts. However, due to different kinematic characteristics, many brain injury risk estimation models are not general…
A comparison of sports-related head accelerations with and without direct head impacts
Samuel J. Raymond, Yuzhe Liu, Nicholas J. Cecchi +9
Concussion and repeated exposure to mild traumatic brain injury are risks for athletes in many sports. While direct head impacts are analyzed to improve the detection and awareness…
Machine-learning-based head impact subtyping based on the spectral densities of the measurable head kinematics
Xianghao Zhan, Yiheng Li, Yuzhe Liu +11
Objective: Traumatic brain injury can be caused by head impacts, but many brain injury risk estimation models are not equally accurate across the variety of impacts that patients m…
Time Window of Head Impact Kinematics Measurement for Calculation of Brain Strain and Strain Rate in American Football
Yuzhe Liu, August G. Domel, Nicholas J. Cecchi +8
Wearable devices have been shown to effectively measure the head movement during impacts in sports like American football. When a head impact occurs, the device is triggered to col…
Predictive Factors of Kinematics in Traumatic Brain Injury from Head Impacts Based on Statistical Interpretation
Xianghao Zhan, Yiheng Li, Yuzhe Liu +12
Brain tissue deformation resulting from head impacts is primarily caused by rotation and can lead to traumatic brain injury. To quantify brain injury risk based on measurements of…
Theoretical and numerical analysis for angular acceleration being determinant of brain strain in mTBI
Yuzhe Liu, Xianghao Zhan, August G. Domel +7
Mild traumatic brain injury (mTBI, also known as concussion) caused by the head impact is a crucial global public health problem, but the physics of mTBI is still unclear. During t…
Relationship between brain injury criteria and brain strain across different types of head impacts can be different
Xianghao Zhan, Yiheng Li, Yuzhe Liu +10
Multiple brain injury criteria (BIC) are developed to quickly quantify brain injury risks after head impacts. These BIC originated from different types of head impacts (e.g., sport…
Deep Learning Head Model for Real-time Estimation of Entire Brain Deformation in Concussion
Xianghao Zhan, Yuzhe Liu, Samuel J. Raymond +6
Objective: Many recent studies have suggested that brain deformation resulting from a head impact is linked to the corresponding clinical outcome, such as mild traumatic brain inju…
A New Open-Access Platform for Measuring and Sharing mTBI Data
August G. Domel, Samuel J. Raymond, Chiara Giordano +22
Despite numerous research efforts, the precise mechanisms of concussion have yet to be fully uncovered. Clinical studies on high-risk populations, such as contact sports athletes,…
Validation and Comparison of Instrumented Mouthguards for Measuring Head Kinematics and Assessing Brain Deformation in Football Impacts
Yuzhe Liu, August G. Domel, Seyed Abdolmajid Yousefsani +4
Because of the relatively rigid coupling between the upper dentition and the skull, instrumented mouthguards have been shown to be a viable way of measuring head impact kinematics…