302 citations · 542 across the 5 of their papers we have counts for
5 papers
eQuilibrator 3.0 -- a platform for the estimation of thermodynamic constants
Moritz E. Beber, Mattia G. Gollub, Dana Mozaffari +2
eQuilibrator (equilibrator.weizmann.ac.il) is a calculator for biochemical equilibrium constants and Gibbs free energies, originally designed as a web-based interface. While the we…
Removing both Internal and Unrealistic Energy-Generating Cycles in Flux Balance Analysis
Elad Noor
Constraint-based stoichiometric models are ubiquitous in metabolic research, with Flux Balance Analysis (FBA) being the most widely used method to describe metabolic phenotypes of…
The protein cost of metabolic fluxes: prediction from enzymatic rate laws and cost minimization
Elad Noor, Avi Flamholz, Arren Bar-Even +3
Bacterial growth depends crucially on metabolic fluxes, which are limited by the cell's capacity to maintain metabolic enzymes. The necessary enzyme amount per unit flux is a major…
The enzyme cost of given metabolic flux distributions, as a function of logarithmic metabolite levels, is convex
Wolfram Liebermeister, Elad Noor
Enzyme costs play a major role in the choice of metabolic routes, both in evolution and bioengineering. Given desired fluxes, necessary enzyme levels can be estimated based on know…
Cross-species analysis traces adaptation of Rubisco towards optimality in a low dimensional landscape
Yonatan Savir, Elad Noor, Ron Milo +1
Rubisco, probably the most abundant protein in the biosphere, performs an essential part in the process of carbon fixation through photosynthesis thus facilitating life on earth. D…