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20242026
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physics.comp-ph2026

Contrastive learning of dynamical representations for enhanced molecular sampling

Kai Zhu, Jintu Zhang, Pietro Novelli +2

Identifying collective variables that capture slow dynamical modes is essential for sampling rare events in complex systems. Existing machine-learning approaches often require pred…

physics.comp-ph2025

Electrochemical Interfaces at Constant Potential: Data-Efficient Transfer Learning for Machine-Learning-Based Molecular Dynamics

Michele Giovanni Bianchi, Michele Re Fiorentin, Francesca Risplendi +4

Simulating electrified metal/water interfaces with explicit solvent under constant potential is essential for understanding electrochemical processes, yet remains prohibitively exp…

physics.comp-ph2025

Enhanced Sampling in the Age of Machine Learning: Algorithms and Applications

Kai Zhu, Enrico Trizio, Jintu Zhang +4

Molecular dynamics simulations hold great promise for providing insight into the microscopic behavior of complex molecular systems. However, their effectiveness is often constraine…

physics.comp-ph2025

Fast and Fourier Features for Transfer Learning of Interatomic Potentials

Pietro Novelli, Giacomo Meanti, Pedro J. Buigues +4

Training machine learning interatomic potentials that are both computationally and data-efficient is a key challenge for enabling their routine use in atomistic simulations. To thi…

physics.comp-ph2024

Descriptors-free Collective Variables From Geometric Graph Neural Networks

Jintu Zhang, Luigi Bonati, Enrico Trizio +4

Enhanced sampling simulations make the computational study of rare events feasible. A large family of such methods crucially depends on the definition of some collective variables…

physics.comp-ph2024

Advanced simulations with PLUMED: OPES and Machine Learning Collective Variables

Enrico Trizio, Andrea Rizzi, Pablo M. Piaggi +2

Many biological processes occur on time scales longer than those accessible to molecular dynamics simulations. Identifying collective variables (CVs) and introducing an external po…