2 papers
cs.LG2024
A Deep Generative Model for the Design of Synthesizable Ionizable Lipids
Yuxuan Ou, Jingyi Zhao, Austin Tripp +2
Lipid nanoparticles (LNPs) are vital in modern biomedicine, enabling the effective delivery of mRNA for vaccines and therapies by protecting it from rapid degradation. Among the co…
cs.LG2024
Generative Model for Synthesizing Ionizable Lipids: A Monte Carlo Tree Search Approach
Jingyi Zhao, Yuxuan Ou, Austin Tripp +2
Ionizable lipids are essential in developing lipid nanoparticles (LNPs) for effective messenger RNA (mRNA) delivery. While traditional methods for designing new ionizable lipids ar…