223 citations · 442 across the 13 of their papers we have counts for
4 papers · 1 filter
Signature of (anti)cooperativity in the stochastic fluctuations of small systems: application to the bacterial flagellar motor
María-José Franco-Oñate, Andrea Parmeggiani, Jérôme Dorignac +6
The cooperative binding of molecular agents onto a substrate is pervasive in living systems. To study whether a system shows cooperativity, one can rely on a fluctuation analysis o…
Physical modeling of ribosomes along messenger RNA: estimating kinetic parameters from ribosome profiling experiments using a ballistic model
Carole Chevalier, Jérôme Dorignac, Yahaya Ibrahim +9
Gene expression consists in the synthesis of proteins from the information encoded on DNA. One of the two main steps of gene expression is the translation of messenger RNA (mRNA) i…
Modeling supercoiled DNA interacting with an anchored cluster of proteins: towards a quantitative estimation of chromosomal DNA supercoiling
Jean-Charles Walter, Thibaut Lepage, Jérôme Dorignac +5
We investigate the measurement of DNA supercoiling density () along chromosomes using interaction frequencies between DNA and DNA-anchored clusters of proteins. Specifically, we…
Looping and Clustering model for the organization of protein-DNA complexes on the bacterial genome
Jean-Charles Walter, Nils-Ole Walliser, Gabriel David +6
The bacterial genome is organized in a structure called the nucleoid by a variety of associated proteins. These proteins can form complexes on DNA that play a central role in vario…