2 papers
q-bio.BM2024
CryoFM: A Flow-based Foundation Model for Cryo-EM Densities
Yi Zhou, Yilai Li, Jing Yuan +1
Cryo-electron microscopy (cryo-EM) is a powerful technique in structural biology and drug discovery, enabling the study of biomolecules at high resolution. Significant advancements…
q-bio.BM2024
ProteinWeaver: A Divide-and-Assembly Approach for Protein Backbone Design
Yiming Ma, Fei Ye, Yi Zhou +3
Nature creates diverse proteins through a 'divide and assembly' strategy. Inspired by this idea, we introduce ProteinWeaver, a two-stage framework for protein backbone design. Our…