40 citations · 127 across the 12 of their papers we have counts for
12 papers
Neurological disorders leading to mechanical dysfunction of the esophagus: an emergent behavior of a neuromechanical dynamical system
Guy Elisha, Sourav Halder, Xinyi Liu +4
An understanding how neurological disorders lead to mechanical dysfunction of the esophagus requires knowledge of the neural circuit of the enteric nervous system. Historically, th…
Direct and retrograde signal propagation in unidirectionally coupled Wilson-Cowan oscillators
Guy Elisha, Richard Gast, Sourav Halder +4
Certain biological systems exhibit both direct and retrograde propagating wave signals, despite unidirectional neural coupling. However, there is no model to explain this. Therefor…
A mechanics--based perspective on the function of human sphincters during functional luminal imaging probe manometry
Guy Elisha, Sourav Halder, Dustin A. Carlson +4
Functional luminal imaging probe (FLIP) is used to measure cross-sectional area (CSA) and pressure at sphincters. It consists of a catheter surrounded by a fluid filled cylindrical…
MRI-MECH: Mechanics-informed MRI to estimate esophageal health
Sourav Halder, Ethan M. Johnson, Jun Yamasaki +4
Dynamic magnetic resonance imaging (MRI) is a popular medical imaging technique to generate image sequences of the flow of a contrast material inside tissues and organs. However, i…
Pressure -- area loop based phenotypic classification and mechanics of esophagogastric junction physiology
Guy Elisha, Sourav Halder, Shashank Acharya +5
The esophagogastric junction (EGJ) is located at the distal end of the esophagus and acts as a valve allowing swallowed materials to enter the stomach and preventing acid reflux. I…
Peristaltic regimes in esophageal transport
Guy Elisha, Shashank Acharya, Sourav Halder +5
A FLIP device gives cross-sectional area along the length of the esophagus and one pressure measurement, both as a function of time. Deducing mechanical properties of the esophagus…
Esophageal virtual disease landscape using mechanics-informed machine learning
Sourav Halder, Jun Yamasaki, Shashank Acharya +6
The pathogenesis of esophageal disorders is related to the esophageal wall mechanics. Therefore, to understand the underlying fundamental mechanisms behind various esophageal disor…
A Fully Resolved Multiphysics Model of Gastric Peristalsis and Bolus Emptying in the Upper Gastrointestinal Tract
Shashank Acharya, Sourav Halder, Wenjun Kou +3
Over the past few decades, in silico modeling of organ systems has significantly furthered our understanding of their physiology and biomechanical function. In this work, we presen…
Mechanics Informed Fluoroscopy of Esophageal Transport
Sourav Halder, Shashank Acharya, Wenjun Kou +3
Fluoroscopy is a radiographic procedure for evaluating esophageal disorders such as achalasia, dysphasia and gastroesophageal reflux disease (GERD). It performs dynamic imaging of…
Pumping Patterns and Work Done during Peristalsis in Finite-length Elastic Tubes
Shashank Acharya, Wenjun Kou, Sourav Halder +4
Balloon dilation catheters are often used to quantify the physiological state of peristaltic activity in tubular organs and comment on their ability to propel fluid which is import…
A continuum mechanics-based musculo-mechanical model for esophageal transport
Wenjun Kou, Boyce E. Griffith, John E. Pandolfino +2
In this work, we extend our previous esophageal transport model using an immersed boundary (IB) method with discrete fiber-based structures, to one using a continuum mechanics-base…
A fully resolved active musculo-mechanical model for esophageal transport
Wenjun Kou, Amneet Pal Singh Bhalla, Boyce E. Griffith +3
Esophageal transport is a physiological process that mechanically transports an ingested food bolus from the pharynx to the stomach via the esophagus, a multi-layered muscular tube…