activity
20152022
most citedA fully resolved active musculo-mechanical model for esophageal transport

40 citations · 123 across the 10 of their papers we have counts for

collaborators

10 papers

physics.med-ph2022

A mechanics--based perspective on the function of human sphincters during functional luminal imaging probe manometry

Guy Elisha, Sourav Halder, Dustin A. Carlson +4

Functional luminal imaging probe (FLIP) is used to measure cross-sectional area (CSA) and pressure at sphincters. It consists of a catheter surrounded by a fluid filled cylindrical…

physics.bio-ph2022

Pressure -- area loop based phenotypic classification and mechanics of esophagogastric junction physiology

Guy Elisha, Sourav Halder, Shashank Acharya +5

The esophagogastric junction (EGJ) is located at the distal end of the esophagus and acts as a valve allowing swallowed materials to enter the stomach and preventing acid reflux. I…

physics.flu-dyn2021

Peristaltic regimes in esophageal transport

Guy Elisha, Shashank Acharya, Sourav Halder +5

A FLIP device gives cross-sectional area along the length of the esophagus and one pressure measurement, both as a function of time. Deducing mechanical properties of the esophagus…

cs.LG2021★ 21 cited

Esophageal virtual disease landscape using mechanics-informed machine learning

Sourav Halder, Jun Yamasaki, Shashank Acharya +6

The pathogenesis of esophageal disorders is related to the esophageal wall mechanics. Therefore, to understand the underlying fundamental mechanisms behind various esophageal disor…

cs.LG2021★ 5 cited

A multi-stage machine learning model on diagnosis of esophageal manometry

Wenjun Kou, Dustin A. Carlson, Alexandra J. Baumann +4

High-resolution manometry (HRM) is the primary procedure used to diagnose esophageal motility disorders. Its interpretation and classification includes an initial evaluation of swa…

physics.flu-dyn2021

A Fully Resolved Multiphysics Model of Gastric Peristalsis and Bolus Emptying in the Upper Gastrointestinal Tract

Shashank Acharya, Sourav Halder, Wenjun Kou +3

Over the past few decades, in silico modeling of organ systems has significantly furthered our understanding of their physiology and biomechanical function. In this work, we presen…

physics.med-ph2020★ 19 cited

Mechanics Informed Fluoroscopy of Esophageal Transport

Sourav Halder, Shashank Acharya, Wenjun Kou +3

Fluoroscopy is a radiographic procedure for evaluating esophageal disorders such as achalasia, dysphasia and gastroesophageal reflux disease (GERD). It performs dynamic imaging of…

physics.flu-dyn2019★ 13 cited

Pumping Patterns and Work Done during Peristalsis in Finite-length Elastic Tubes

Shashank Acharya, Wenjun Kou, Sourav Halder +4

Balloon dilation catheters are often used to quantify the physiological state of peristaltic activity in tubular organs and comment on their ability to propel fluid which is import…

physics.comp-ph2016★ 25 cited

A continuum mechanics-based musculo-mechanical model for esophageal transport

Wenjun Kou, Boyce E. Griffith, John E. Pandolfino +2

In this work, we extend our previous esophageal transport model using an immersed boundary (IB) method with discrete fiber-based structures, to one using a continuum mechanics-base…

physics.comp-ph2015★ 40 cited

A fully resolved active musculo-mechanical model for esophageal transport

Wenjun Kou, Amneet Pal Singh Bhalla, Boyce E. Griffith +3

Esophageal transport is a physiological process that mechanically transports an ingested food bolus from the pharynx to the stomach via the esophagus, a multi-layered muscular tube…