14 papers
Anatomically Guided Latent Diffusion for Brain MRI Progression Modeling
Cheng Wan, Bahram Jafrasteh, Ehsan Adeli +2
Accurately modeling longitudinal brain MRI progression is crucial for understanding neurodegenerative diseases and predicting individualized structural changes. Existing state-of-t…
Human-like Content Analysis for Generative AI with Language-Grounded Sparse Encoders
Yiming Tang, Arash Lagzian, Srinivas Anumasa +9
The rapid development of generative AI has transformed content creation, communication, and human development. However, this technology raises profound concerns in high-stakes doma…
Modality-Aware and Anatomical Vector-Quantized Autoencoding for Multimodal Brain MRI
Mingjie Li, Edward Kim, Yue Zhao +2
Learning a robust Variational Autoencoder (VAE) is a fundamental step for many deep learning applications in medical image analysis, such as MRI synthesizes. Existing brain VAEs pr…
A Generative Foundation Model for Multimodal Histopathology
Jinxi Xiang, Mingjie Li, Siyu Hou +9
Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to…
Latent Causal Modeling for 3D Brain MRI Counterfactuals
Wei Peng, Tian Xia, Fabio De Sousa Ribeiro +5
The number of samples in structural brain MRI studies is often too small to properly train deep learning models. Generative models show promise in addressing this issue by effectiv…
TherapyGym: Evaluating and Aligning Clinical Fidelity and Safety in Therapy Chatbots
Fangrui Huang, Souhad Chbeir, Arpandeep Khatua +8
Large language models (LLMs) are increasingly used for mental-health support; yet prevailing evaluation methods--fluency metrics, preference tests, and generic dialogue benchmarks-…