activity
20112025
most citedA mathematical model of granulopoiesis incorporating the negative feedback dynamics and kinetics of G-CSF/neutrophil binding and internalisation

71 citations · 328 across the 17 of their papers we have counts for

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11 papers · 1 filter

math.DS2025

Practicalities of State-Dependent and Threshold Delay Differential Equations

A. R. Humphries, A. S. Eremin, Z. Wang

Delays are ubiquitous in applied problems, but often do not arise as the simple constant discrete delays that analysts and numerical analysts like to treat. In this chapter we show…

math.DS2025

Seasonal Forcing Dominated Dynamics of a piecewise smooth Ghil-Zaliapin-Thompson ENSO model

Samuel Bolduc-St-Aubin, Antony R. Humphries

The Ghil-Zaliapin-Thompson (GZT) model, a scalar delay differential equation with periodic forcing and time-delayed feedback, captures key features of the El Nino-Southern Oscillat…

math.DS2024★ 1 cited

Dynamics of a state-dependent delay-differential equation

Tomas Gedeon, Antony R. Humphries, Michael C. Mackey +2

We present a detailed study of a scalar differential equation with threshold state-dependent delayed feedback. This equation arises as a simplification of a gene regulatory model.…

math.DS2021★ 1 cited

Nonlinear effects of instantaneous and delayed state dependence in a delayed feedback loop

Antony R. Humphries, Bernd Krauskopf, Stefan Ruschel +1

We study a scalar, first-order delay differential equation (DDE) with instantaneous and state-dependent delayed feedback, which itself may be delayed. The state dependence introduc…

math.DS2021★ 17 cited

Operon Dynamics with State Dependent Transcription and/or Translation Delays

Tomas Gedeon, Antony R. Humphries, Michael C. Mackey +3

Transcription and translation retrieve and operationalize gene encoded information in cells. These processes are not instantaneous and incur significant delays. In this paper we st…

math.DS2017★ 26 cited

Dynamics of a Mathematical Hematopoietic Stem-Cell Population Model

Daniel C. De Souza, Antony R. Humphries

We explore the bifurcations and dynamics of a scalar differential equation with a single constant delay which models the population of human hematopoietic stem cells in the bone ma…

math.DS2017★ 7 cited

Generalised Lyapunov-Razumikhin techniques for scalar state-dependent delay differential equations

F. M. G. Magpantay, A. R. Humphries

We present generalised Lyapunov-Razumikhin techniques for establishing global asymptotic stability of steady-state solutions of scalar delay differential equations. When global asy…

math.DS2016★ 34 cited

Resonance phenomena in a scalar delay differential equation with two state-dependent delays

R. C. Calleja, A. R. Humphries, B. Krauskopf

We study a scalar DDE with two delayed feedback terms that depend linearly on the state. The associated constant-delay DDE, obtained by freezing the state dependence, is linear and…

math.DS2015★ 3 cited

Lyapunov-Razumikhin techniques for state-dependent delay differential equations

A. R. Humphries, F. M. G. Magpantay

We present Lyapunov stability and asymptotic stability theorems for steady state solutions of general state-dependent delay differential equations (DDEs) using Lyapunov-Razumikhin…

math.DS2014★ 15 cited

Periodic Solutions of a Singularly Perturbed Delay Differential Equation With Two State-Dependent Delays

A. R. Humphries, D. A. Bernucci, R. Calleja +2

Periodic orbits and associated bifurcations of singularly perturbed state-dependent delay differential equations (DDEs) are studied when the profiles of the periodic orbits contain…

math.DS2011★ 39 cited

Computing Invariant Manifolds and Connecting Orbits in the Circular Restricted Three Body Problem

Renato C. Calleja, Eusebius J. Doedel, Antony R. Humphries +2

We demonstrate the remarkable effectiveness of boundary value formulations coupled to numerical continuation for the computation of stable and unstable manifolds in systems of ordi…