87 citations · 265 across the 9 of their papers we have counts for
9 papers
Modelling the role of flux density and coating on nanoparticle internalization by tumor cells under centrifugation
Gabriel F. Calvo, Belén Cortés-Llanos, Juan Belmonte-Beitia +2
Nanoparticle (NP)-based applications are becoming increasingly important in the biomedical field. However, understanding the interactions of NPs with biofluids and cells is a major…
Modelling the effect of vascular status on tumour evolution and outcome after thermal therapy
Jesús J. Bosque, Gabriel F. Calvo, María Cruz Navarro
Microscale oxygenation plays a prominent role in tumour progression. Spatiotemporal variability of oxygen distribution in the tumour microenvironment contributes to cellular hetero…
Universal scaling laws rule explosive growth inhuman cancers
Víctor M. Pérez-García, Gabriel F. Calvo, Jesús J. Bosque +24
Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is a surprising fact that they often obey the so-call…
CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
Odelaisy Leon-Triana, Soukaina Sabir, Gabriel F. Calvo +7
Immunotherapies use components of the patient immune system to selectively target cancer cells. The use of CAR T cells to treat B-cell malignancies --leukaemias and lymphomas-- is…
Effective Particle Methods for Fisher-Kolmogorov Equations: Theory and Applications to Brain Tumor Dynamics
Juan Belmonte-Beitia, Gabriel F. Calvo, Victor M. Perez-Garcia
Extended systems governed by partial differential equations can, under suitable conditions, be approximated by means of sets of ordinary differential equations for global quantitie…
Combined therapies of antithrombotics and antioxidants delay in silico brain tumor progression
Alicia Martínez-González, Mario Durán-Prado, Gabriel F. Calvo +3
Glioblastoma multiforme, the most frequent type of primary brain tumor, is a rapidly evolving and spatially heterogeneous high-grade astrocytoma that presents areas of necrosis, hy…
Hypoxic Cell Waves around Necrotic Cores in Glioblastoma: A Biomathematical Model and its Therapeutic Implications
Alicia Martínez-González, Gabriel F. Calvo, Luis A. Pérez Romasanta +1
Glioblastoma is a rapidly evolving high-grade astrocytoma that is distinguished pathologically from lower grade gliomas by the presence of necrosis and microvascular hiperplasia. N…
Bright Solitary Waves in Malignant Gliomas
Víctor M. Pérez-García, Gabriel F. Calvo, Juan Belmonte-Beitia +2
We put forward a nonlinear wave model describing the fundamental physio-pathologic features of an aggressive type of brain tumors: glioblastomas. Our model accounts for the invasio…
Exact Bright and Dark Spatial Soliton Solutions in Saturable Nonlinear Media
Gabriel F. Calvo, Juan Belmonte-Beitia, Victor M. Perez-Garcia
We present exact analytical bright and dark (black and grey) solitary wave solutions of a nonlinear Schrodinger-type equation describing the propagation of spatial beams in media e…