most citedPre-training of Graph Neural Network for Modeling Effects of Mutations on Protein-Protein Binding Affinity

141 citations · 141 across the 1 of their papers we have counts for

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1 paper

q-bio.BM2020★ 141 cited

Pre-training of Graph Neural Network for Modeling Effects of Mutations on Protein-Protein Binding Affinity

Xianggen Liu, Yunan Luo, Sen Song +1

Modeling the effects of mutations on the binding affinity plays a crucial role in protein engineering and drug design. In this study, we develop a novel deep learning based framewo…