5 papers
Open-source MRI-informed computational model of human cortical folding
Anne Kerachni, Thomas Lavigne, Stéphane Urcun +3
The human cerebral cortex, initially smooth, progressively folds during fetal brain development in utero, giving rise to cortical convolutions. Atypical cortical folding patterns c…
An MRI-informed poromechanical model for organ-scale prediction of glioma growth
Meryem Abbad Andaloussi, Stephane Urcun, David A. Hormuth +5
Gliomas constitute one of the most aggressive and heterogeneous forms of brain tumors, posing major challenges for understanding their biology and developing effective treatments.…
Hierarchical poromechanical approach to investigate the impact of mechanical loading on human skin micro-circulation
Thomas Lavigne, Stéphane Urcun, Bérengère Fromy +6
Research on human skin anatomy reveals its complex multi-scale, multi-phase nature, with up to 70% of its composition being bounded and free water. Fluid movement plays a key role…
Synthetic Porous Microstructures: Automatic Design, Simulation, and Permeability Analysis
Thomas Lavigne, Camilo Andrés Suarez Afanador, Anas Obeidat +1
This study introduces an open-source computational framework for the generation and permeability evaluation of synthetic porous media. The proposed methodology integrates crystallo…
Poromechanical modelling of the time-dependent response of in vivo human skin during extension
Thomas Lavigne, Stéphane Urcun, Emmanuelle Jacquet +6
This paper proposes a proof of concept application of a biphasic constitutive model to identify the mechanical properties of in vivo human skin under extension. Although poromechan…