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Quantification of myosin distribution predicts global morphogenetic flow in the fly embryo
Sebastian J Streichan, Matthew F Lefebvre, Nicholas Noll +2
During embryogenesis tissue layers continuously rearrange and fold into specific shapes. Developmental biology identified patterns of gene expression and cytoskeletal regulation un…
Leaf growth is conformal
Karen Alim, Shahaf Armon, Boris I. Shraiman +1
Growth pattern dynamics lie at the heart of morphogenesis. Here, we investigate the growth of plant leaves. We compute the conformal transformation that maps the contour of a leaf…
Active Tension Network model reveals an exotic mechanical state realized in epithelial tissues
Nicholas Noll, Madhav Mani, Idse Heemskerk +2
It is now widely recognized that mechanical interactions between cells play a crucial role in epithelial morphogenesis, yet understanding the mechanisms through which stress and de…
Collective and single cell behavior in epithelial contact inhibition
Alberto Puliafito, Lars Hufnagel, Pierre Neveu +4
Control of cell proliferation is a fundamental aspect of tissue physiology central to morphogenesis, wound healing and cancer. Although many of the molecular genetic factors are no…