4 papers
A safety-oriented hypothetico-deductive framework for AI-assisted differential diagnosis
Fan Ma, Mauro Giuffrè, Donald Wright +12
Diagnostic error is a major threat to patient safety, yet current large language model (LLM) systems often treat diagnosis as a one-shot prediction task, lacking safeguards against…
Teaching agentic AI to learn expert reasoning for rare disease diagnosis
Minh-Ha Nguyen, Erica Gray, Bryce A. Schuler +17
Rare disease diagnosis depends on expert reasoning that is scarce and difficult to transfer; off-the-shelf large language models (LLMs) rank the correct disease first in only 35.4%…
Foundation Models to Unlock Real-World Evidence from Nationwide Medical Claims
Fan Ma, Yuntian Liu, Xiang Lan +22
Evidence derived from large-scale real-world data (RWD) is increasingly informing regulatory evaluation and healthcare decision-making. Administrative claims provide population-sca…
EHRNavigator: A Multi-Agent System for Patient-Level Clinical Question Answering over Heterogeneous Electronic Health Records
Lingfei Qian, Mauro Giuffre, Yan Wang +11
Clinical decision-making increasingly relies on timely and context-aware access to patient information within Electronic Health Records (EHRs), yet most existing natural language q…