3 papers
physics.optics2026
Physics-Aligned Deep Learning Enables SERS Resolving and Sequencing of Dynamic Single-Molecule DNA Oligomers in Plasmonic Nanocavity
Kuo Zhan, Peilin Xin, Yingqi Zhao +7
Single-molecule surface-enhanced Raman spectroscopy (SM-SERS) captures dynamic molecular behavior with ultrahigh sensitivity, but its biopolymer analysis is hindered by strong spec…
physics.app-ph2026
SERS study of single-live-cell electrical permeabilization dynamics via plasmonic nanotubes
Yuge Liang, Peilin Xin, Enock Adjei Agyekum +7
There is a growing demand for minimally invasive methods to analyze intracellular processes and signaling activities in individual living cells, including the identification of tum…
physics.bio-ph2026
Label-free SERS Discrimination of Native Proline Hydroxylation at Single-molecule peptide by Deep Learning-assisted plasmonic nanopore
Yingqi Zhao, Kuo Zhan, Pei-Lin Xin +6
Post-translational modifications (PTMs) play essential roles in regulating protein structure, function, and cellular signalling. However, peptide level discrimination of hydroxylat…