142 citations · 147 across the 3 of their papers we have counts for
3 papers
Membraneless organelles formed by liquid-liquid phase separation increase bacterial fitness
Xin Jin, Ji-Eun Lee, Charley Schaefer +10
Liquid-liquid phase separation is emerging as a crucial phenomenon in several fundamental cell processes. A range of eukaryotic systems exhibit liquid condensates. However, their f…
Single-molecule imaging of DNA gyrase activity in living Escherichia coli
Mathew Stracy, Adam J. M. Wollman, Elzbieta Kaja +9
Bacterial DNA gyrase introduces negative supercoils into chromosomal DNA and relaxes positive supercoils introduced by replication and transiently by transcription. Removal of thes…
H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation
Ji-Eun Lee, Chaochen Wang, Shiliyang Xu +7
Enhancers play a central role in cell-type-specific gene expression and are marked by H3K4me1/2. Active enhancers are further marked by H3K27ac. However, the methyltransferases res…