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20182025
most citedPost-randomization Biomarker Effect Modification in an HIV Vaccine Clinical Trial

1 citations · 3 across the 6 of their papers we have counts for

collaborators

6 papers

stat.ME2025

Evaluating Informative Cluster Size in Cluster Randomized Trials

Bryan S. Blette, Zhe Chen, Brennan C. Kahan +3

In cluster randomized trials, the average treatment effect among individuals (i-ATE) can be different from the cluster average treatment effect (c-ATE) when informative cluster siz…

stat.ME2024

An overview of methods for receiver operating characteristic analysis, with an application to SARS-CoV-2 vaccine-induced humoral responses in solid organ transplant recipients

Nathaniel P. Dowd, Bryan Blette, James D. Chappell +2

Receiver operating characteristic (ROC) analysis is a tool to evaluate the capacity of a numeric measure to distinguish between groups, often employed in the evaluation of diagnost…

stat.ME2024

Addressing Confounding and Continuous Exposure Measurement Error Using Corrected Score Functions

Brian D. Richardson, Bryan S. Blette, Peter B. Gilbert +1

Confounding and exposure measurement error can introduce bias when drawing inference about the marginal effect of an exposure on an outcome of interest. While there are broad metho…

stat.ME2023★ 1 cited

Demystifying estimands in cluster-randomised trials

Brennan C Kahan, Bryan Blette, Michael Harhay +4

Estimands can help clarify the interpretation of treatment effects and ensure that estimators are aligned to the study's objectives. Cluster randomised trials require additional at…

stat.ME2022★ 1 cited

Assessing treatment effect heterogeneity in the presence of missing effect modifier data in cluster-randomized trials

Bryan S. Blette, Scott D. Halpern, Fan Li +1

Understanding whether and how treatment effects vary across subgroups is crucial to inform clinical practice and recommendations. Accordingly, the assessment of heterogeneous treat…

stat.AP2018★ 1 cited

Post-randomization Biomarker Effect Modification in an HIV Vaccine Clinical Trial

Peter B. Gilbert, Bryan S. Blette, Bryan E. Shepherd +1

While the HVTN 505 trial showed no overall efficacy of the tested vaccine to prevent HIV infection over placebo, previous studies, biological theories, and the finding that immune…