3 papers
q-bio.GN2018
An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research
Franck Court, Philippe Arnaud
CpG islands (CGI) marked by bivalent chromatin in stem cells are believed to be more prone to aberrant DNA methylation in tumor cells. The robustness and genome-wide extent of this…
q-bio.GN2018
Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive
Stéphanie Maupetit-Méhouas, Bertille Montibus, David Nury +11
Parental allele-specific expression of imprinted genes is mediated by imprinting control regions (ICRs) that are constitutively marked by DNA methylation imprints on the maternal o…
q-bio.GN2018
The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma
Ana Xavier-Magalhães, Céline Gonçalves, Anne Fogli +17
The lncRNA HOTAIR has been implicated in several human cancers. Here, we evaluated the molecular alterations and upstream regulatory mechanisms of HOTAIR in glioma, the most common…