132 citations · 174 across the 7 of their papers we have counts for
3 papers · 1 filter
Quantifying the performance of high-throughput directed evolution protocols
Adèle Dramé-Maigné, Anton Zadorin, Iaroslava Golovkova +1
Most protocols for the high-throughput directed evolution of enzymes rely on random encapsulation to link phenotype and genotype. In order to optimize these approaches, or compare…
Selection strategies for randomly partitioned genetic replicators
Anton S. Zadorin, Yannick Rondelez
The amplification cycle of many replicators (natural or artificial) involves the usage of a host compartment, inside of which the replicator express phenotypic compounds necessary…
Natural selection in compartmentalized environment with reshuffling
Anton S. Zadorin, Yannick Rondelez
The emerging field of high-throughput compartmentalized in vitro evolution is a promising new approach to protein engineering. In these experiments, libraries of mutant genotypes a…