32 citations · 61 across the 11 of their papers we have counts for
11 papers
FLASH-enabled Proton SBRT for a challenging case of spine metastasis
S. Wuyckens, M. Chocan Vera, R. Nilsson +5
The FLASH effect, characterized by potential sparing of organs at risk (OAR) through ultra-high dose rate irradiation, has garnered significant attention for its capability to addr…
Proton arc therapy plan optimization with energy layer pre-selection driven by organ at risk sparing and delivery time
S. Wuyckens, G. Janssens, M. Chocan Vera +5
Objective. As proton arc therapy (PAT) approaches clinical implementation, optimizing treatment plans for this innovative delivery modality remains challenging, especially in addre…
A dosimetric and robustness analysis of Proton Arc Therapy (PAT) with Early Energy Layer and Spot Assignment (ELSA) for lung cancer versus conventional Intensity modulated therapy (IMPT)
Macarena S. Chocan, Sophie Wuyckens, Damien Dasnoy +6
Background and purpose: IMPT faces challenges in lung cancer treatment, like maintaining plan robustness for moving tumors against setup, range errors, and interplay effects. Proto…
Efficient proton arc optimization and delivery through energy layer pre-selection and post-filtering
S. Wuyckens, V. Wase, O. Marthin +7
Proton arc therapy (PAT) has emerged as a promising approach for improving dose distribution, but also enabling simpler and faster treatment delivery in comparison to conventional…
Beamlet-free optimization for Monte Carlo based treatment planning in proton therapy
D. Pross, S. Wuyckens, S. Deffet +3
Background: Dose calculation and optimization algorithms in proton therapy treatment planning often have high computational requirements regarding time and memory. This can hinder…
Optimization of pencil beam scanning pattern for FLASH proton therapy
Sylvain Deffet, Edmond Sterpin
Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation ther…
Optimization of patient-specific range modulators for conformal FLASH proton therapy
Sylvain Deffet, Kevin Souris, Edmond Sterpin
Purpose: A promising approach to enable FLASH conformal proton therapy is to passively degrade a single energy layer using a patient-specific range modulator. We propose an innovat…
Definition of dose rate for FLASH pencil-beam scanning proton therapy: A comparative study
Sylvain Deffet, Valentin Hamaide, Edmond Sterpin
Purpose: Highlight the distinctions, both in terms of concept and numerical values, of the various definitions that can be established for the dose rate in PBS proton therapy. Meth…
OpenTPS -- Open-source treatment planning system for research in proton therapy
S. Wuyckens, D. Dasnoy, G. Janssens +9
Introduction. Treatment planning systems (TPS) are an essential component for simulating and optimizing a radiation therapy treatment before administering it to the patient. It ens…
Three-Dimensional Dose Prediction for Lung IMRT Patients with Deep Neural Networks: Robust Learning from Heterogeneous Beam Configurations
Ana M. Barragan-Montero, Dan Nguyen, Weiguo Lu +4
The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods only use patient anato…
A method to optimize patient specific HU-SP calibration curve from proton range measurements
Jaroslav Albert, Rudi Labarbe, Edmond Sterpin
Proton radiotherapy promises accurate dose delivery to a tumor and minimal dose deposition to all other tissues. However, in practice the planned dose distribution may not conform…