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q-bio.QM2018
Essential guidelines for computational method benchmarking
Lukas M. Weber, Wouter Saelens, Robrecht Cannoodt +6
In computational biology and other sciences, researchers are frequently faced with a choice between several computational methods for performing data analyses. Benchmarking studies…
q-bio.QM2013★ 9 cited
Robustly detecting differential expression in RNA sequencing data using observation weights
Xiaobei Zhou, Helen Lindsay, Mark D. Robinson
A popular approach for comparing gene expression levels between (replicated) conditions of RNA sequencing data relies on counting reads that map to features of interest. Within suc…