activity
20182025
most citedQuantifying material properties of cell monolayers by analyzing integer topological defects

51 citations · 111 across the 10 of their papers we have counts for

collaborators

10 papers

physics.bio-ph2025

Defect states in compressible active polar fluids with turnover

Ludovic Dumoulin, Carles Blanch-Mercader, Karsten Kruse

Biological active matter like the cytoskeleton or tissues are characterized by their ability to transform chemical energy into mechanical stress. In addition, it often exhibits ori…

cond-mat.soft2025★ 1 cited

The importance of being discrete -- An agent-based model for active nematics and more

Mathieu Dedenon, Carles Blanch-Mercader, Karsten Kruse +1

We propose an agent-based model of active flexible rods. Inspired by cytoskeletal flows, we introduce activity by an internal flow that contributes to the dissipative forces. The a…

cond-mat.soft2024

Effective viscosity of a two dimensional passive suspension in a liquid crystal solvent

S. Dang, C. Blanch-Mercader, L. Berlyand

Suspension of particles in a fluid solvent are ubiquitous in nature, for example, water mixed with sugar or bacteria self-propelling through mucus. Particles create local flow pert…

q-bio.TO2024

Src Kinase Slows Collective Rotation of Confined Epithelial Cell Monolayers

Nastassia Pricoupenko, Flavia Marsigliesi, Philippe Marcq +2

Collective cell migration is key during development, wound healing and metastasis and relies on coordinated cell behaviors at the group level. Src kinase is a key signalling protei…

physics.bio-ph2024★ 14 cited

Emergence of bidirectional cell laning from collective contact guidance

Mathilde Lacroix, Bart Smeets, Carlès Blanch-Mercader +5

Directed collective cell migration is central in morphogenesis, wound healing and cancer progression1,2. Although it is well-accepted that the molecular anisotropy of the micro-env…

cond-mat.soft2023★ 2 cited

Passive defect driven morphogenesis in nematic membranes

D. J. G. Pearce, C. Thibault, Q. Chaboche +1

Topological defects are ubiquitous on surfaces with orientational order fields. Here, we study equilibrium states generated by the feedback between geometry and nematic order on fl…

cond-mat.soft2023★ 5 cited

Density-polarity coupling in confined active polar films: asters, spirals, and biphasic orientational phases

Mathieu Dedenon, Claire A. Dessalles, Pau Guillamat +3

Topological defects in active polar fluids can organise spontaneous flows and influence macroscopic density patterns. Both of them play, for example, an important role during anima…

cond-mat.soft2020★ 38 cited

Integer topological defects of cell monolayers -- mechanics and flows

Carles Blanch-Mercader, Pau Guillamat, Aurélien Roux +1

Monolayers of anisotropic cells exhibit long-ranged orientational order and topological defects. During the development of organisms, orientational order often influences morphogen…

cond-mat.soft2020★ 51 cited

Quantifying material properties of cell monolayers by analyzing integer topological defects

Carles Blanch-Mercader, Pau Guillamat, Aurélien Roux +1

In developing organisms, internal cellular processes generate mechanical stresses at the tissue scale. The resulting deformations depend on the material properties of the tissue, w…

q-bio.TO2018

Collective stresses drive competition between monolayers of normal and Ras-transformed cells

Sarah Moitrier, Carles Blanch-Mercader, Simon Garcia +6

We study the competition for space between two cell lines that differ only in the expression of the Ras oncogene. The two cell populations are initially separated and set to migrat…