3 papers
stat.ME2022
An Adaptive and Robust Method for Multi-trait Analysis of Genome-wide Association Studies Using Summary Statistics
Qiaolan Deng, Chi Song, Shili Lin
Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with human traits or diseases in the past decade. Nevertheless, much of the heritabi…
stat.ME2020
Multiple-trait Adaptive Fisher's Method for Genome-wide Association Studies
Qiaolan Deng, Chi Song
In genome-wide association studies (GWASs), there is an increasing need for detecting the associations between a genetic variant and multiple traits. In studies of complex diseases…
stat.ME2018
Association Analysis of Common and Rare SNVs using Adaptive Fisher Method to Detect Dense and Sparse Signals
XIaoyu Cai, Lo-Bin Chang, Chi Song
The development of next generation sequencing (NGS) technology and genotype imputation methods enabled researchers to measure both common and rare variants in genome-wide associati…