49 citations · 49 across the 5 of their papers we have counts for
6 papers
Be Prospective, Not Retrospective: A Philosophy for Advancing Reproducibility in Modern Biological Research
Griffin Chure
The ubiquity of computation in modern scientific research inflicts new challenges for reproducibility. While most journals now require code and data be made available, the standard…
The Anthropocene by the Numbers: A Quantitative Snapshot of Humanity's Influence on the Planet
Griffin Chure, Rachel A. Banks, Avi I. Flamholz +6
The presence and action of humans on Earth has exerted a strong influence on the evolution of the planet over the past 10,000 years, the consequences of which are now bec…
The Energetics of Molecular Adaptation in Transcriptional Regulation
Griffin Chure, Manuel Razo-Mejia, Nathan M. Belliveau +5
Mutation is a critical mechanism by which evolution explores the functional landscape of proteins. Despite our ability to experimentally inflict mutations at will, it remains diffi…
Figure 1 Theory Meets Figure 2 Experiments in the Study of Gene Expression
Rob Phillips, Nathan M. Belliveau, Griffin Chure +3
It is tempting to believe that we now own the genome. The ability to read and re-write it at will has ushered in a stunning period in the history of science. Nonetheless, there is…
Connecting the dots between mechanosensitive channel abundance, osmotic shock, and survival at single-cell resolution
Griffin Chure, Heun Jin Lee, Rob Phillips
Rapid changes in extracellular osmolarity are one of many insults microbial cells face on a daily basis. To protect against such shocks, Escherichia coli and other microbes express…
Tuning transcriptional regulation through signaling: A predictive theory of allosteric induction
Manuel Razo-Mejia, Stephanie L. Barnes, Nathan M. Belliveau +4
Allosteric regulation is found across all domains of life, yet we still lack simple, predictive theories that directly link the experimentally tunable parameters of a system to its…