3 citations · 6 across the 4 of their papers we have counts for
4 papers
BaySize: Bayesian Sample Size Planning for Phase I Dose-Finding Trials
Xiaolei Lin, Jiaying Lyu, Shijie Yuan +2
We propose BaySize, a sample size calculator for phase I clinical trials using Bayesian models. BaySize applies the concept of effect size in dose finding, assuming the MTD is defi…
Hi3+3: A Model-Assisted Dose-Finding Design Borrowing Historical Data
Yunshan Duan, Sue-Jane Wang, Yuan Ji
Background -- In phase I clinical trials, historical data may be available through multi-regional programs, reformulation of the same drug, or previous trials for a drug under the…
The i3+3 Design for Phase I Clinical Trials
Meizi Liu, Sue-Jane Wang, Yuan Ji
Purpose: The 3+3 design has been shown to be less likely to achieve the objectives of phase I dose-finding trials when compared with more advanced model-based designs. One major cr…
A Bayesian Interval Dose-Finding Design Addressing Ockham's Razor: mTPI-2
Wentian Guo, Sue-Jane Wang, Shengjie Yang +2
There has been an increasing interest in using interval-based Bayesian designs for dose finding, one of which is the modified toxicity probability interval (mTPI) method. We show t…