22 citations · 56 across the 7 of their papers we have counts for
7 papers
Vagus nerve manipulation and microglial plasticity in the prenatal brain
Marc Courchesne, Colin Wakefield, Karen Nygard +5
The efferent and afferent effects of the vagus nerve on the developing brain have remained enigmatic. Here we review the evidence of such effects on microglial plasticity in the sh…
The vagus nerve regulates immunometabolic homeostasis in the ovine fetus near term: impact on terminal ileum
Mingju Cao, Shikha Kuthiala, Keven Jason Jean +8
The contribution of the vagus nerve to inflammation and glucosensing in the fetus is not understood. We hypothesized that vagotomy (Vx) will trigger a rise in systemic glucose leve…
Recording and manipulation of vagus nerve electrical activity in chronically instrumented unanesthetized near term fetal sheep
Aude Castel, Patrick M. Burns, Javier Benito +9
Background: The chronically instrumented pregnant sheep has been used as a model of human fetal development and responses to pathophysiologic stimuli. This is due to the unique ame…
The neonatal sepsis is diminished by cervical vagus nerve stimulation and tracked non-invasively by ECG: a preliminary report in the piglet model
Aude Castel, Patrick Burns, Colin Wakefield +8
An electrocardiogram (ECG)-derived heart rate variability (HRV) index reliably tracks the inflammatory response induced by low-dose lipopolysaccharide (LPS) in near-term sheep fetu…
Vagal contributions to fetal heart rate variability: an omics approach
Christophe L. Herry, Patrick Burns, Andre Desrochers +5
Fetal heart rate variability (fHRV) is an important indicator of health and disease, yet its physiological origins, neural contributions in particular, are not well understood. We…
Alpha7 nicotinic acetylcholine receptor signaling modulates ovine fetal brain astrocytes transcriptome in response to endotoxin
M. Cao, J. W. MacDonald, H. L. Liu +12
Neuroinflammation in utero may result in lifelong neurological disabilities. Astrocytes play a pivotal role, but the mechanisms are poorly understood. No early postnatal treatment…
Non-invasive acquisition of fetal ECG from the maternal xyphoid process: a feasibility study in pregnant sheep and a call for open data sets
C Shen, MG Frasch, HT Wu +5
Objective: The utility of fetal heart rate (FHR) monitoring can only be achieved with an acquisition sampling rate that preserves the underlying physiological information on the mi…