56 citations · 94 across the 5 of their papers we have counts for
5 papers
A model of tuberculosis progression using CompuCell3D
James W. G. Doran, Christopher F. Rowlatt, Gibin G. Powathil +2
Tuberculosis (TB) is an airborne disease caused by the bacterium Mycobacterium tuberculosis (M. tb). Prior to the COVID-19 pandemic, TB was the leading cause of death from an infec…
Uncertainty and Sensitivity Analyses Methods for Agent-Based Mathematical Models: An Introductory Review
Sara Hamis, Stanislav Stratiev, Gibin G Powathil
Multiscale, agent-based mathematical models of biological systems are often associated with model uncertainty and sensitivity to parameter perturbations. Here, three uncertainty an…
Hybrid Modelling in Oncology: Sucesses, Challenges and Hopes
Angélique Stéphanou, Pascal Ballet, Gibin Powathil
In this review we make the statement that hybrid models in oncology are required as a mean for enhanced data integration. In the context of systems oncology, experimental and clini…
Bystander effects and their implications for clinical radiation therapy: Insights from multiscale in silico experiments
Gibin G Powathil, Alastair J Munro, Mark AJ Chaplain +1
Radiotherapy is a commonly used treatment for cancer and is usually given in varying doses. At low radiation doses relatively few cells die as a direct response to radiation but se…
Investigating the development of chemotherapeutic drug resistance in cancer: A multiscale computational study
Gibin G Powathil, Mark AJ Chaplain, Maciej Swat
Chemotherapy is one of the most important therapeutic options used to treat human cancers, either alone or in combination with radiation therapy and surgery. Recent studies have in…