3 papers
stat.ME2026
Global testing of SNP-methylation interactions on binary phenotypes via a logistic functional regression model
Yvelin Gansou, Karim Oualkacha, Marzia Angela Cremona +1
Understanding how genetic and epigenetic factors jointly influence binary health outcomes remains a major challenge in biomedical research. We propose a global test for the overall…
stat.ME2025
A Functional Approach to Testing Overall Effect of Interaction Between DNA Methylation and SNPs
Yvelin Gansou, Karim Oualkacha, Marzia Angela Cremona +1
We introduce a test for the overall effect of interaction between DNA methylation and a set of single nucleotide polymorphisms (SNPs) on a quantitative phenotype. The developed inf…
stat.ME2025
Penalized generalized linear mixed models for longitudinal outcomes in genetic association studies
Julien St-Pierre, Sahir Rai Bhatnagar, Massimiliano Orri +3
This work is motivated by analyses of longitudinal data collected from participants in the Quebec Longitudinal Study of Child Development (QLSCD) and the Quebec Newborn Twin Study…