23 papers
SAGEAgent: A Self-Evolving Agent for Cost-Aware Modality Acquisition in Multimodal Survival Prediction
Chongyu Qu, Can Cui, Zhengyi Lu +8
Does every cancer patient truly need a complete diagnostic workup for accurate survival prediction? In multimodal clinical oncology, diagnostic modalities follow a clinically manda…
MORI-Seg: Learning Morphological Geometry for Instance Segmentation without Instance Annotations
Leiyue Zhao, Tianyu Shi, Daniel Reisenbuchler +12
Instance-level quantification of kidney functional units is essential for morphometric analysis, yet most publicly available pathology datasets provide only semantic segmentation a…
An Interpretable Vision Transformer as a Fingerprint-Based Diagnostic Aid for Kabuki and Wiedemann-Steiner Syndromes
Marilyn Lionts, Arnhildur Tomasdottir, Viktor I. Agustsson +3
Kabuki syndrome (KS) and Wiedemann-Steiner syndrome (WSS) are rare but distinct developmental disorders that share overlapping clinical features, including neurodevelopmental delay…
Explainable Pathomics Feature Visualization via Correlation-aware Conditional Feature Editing
Yuechen Yang, Junlin Guo, Ruining Deng +9
Pathomics is a recent approach that offers rich quantitative features beyond what black-box deep learning can provide, supporting more reproducible and explainable biomarkers in di…
SCR2-ST: Combine Single Cell with Spatial Transcriptomics for Efficient Active Sampling via Reinforcement Learning
Junchao Zhu, Ruining Deng, Junlin Guo +13
Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data…
HistoWAS: A Pathomics Framework for Large-Scale Feature-Wide Association Studies of Tissue Topology and Patient Outcomes
Yuechen Yang, Junlin Guo, Yanfan Zhu +10
High-throughput "pathomic" analysis of Whole Slide Images (WSIs) offers new opportunities to study tissue characteristics and for biomarker discovery. However, the clinical relevan…