2 papers
q-bio.MN2020
Computation of single-cell metabolite distributions using mixture models
Mona K Tonn, Philipp Thomas, Mauricio Barahona +1
Metabolic heterogeneity is widely recognised as the next challenge in our understanding of non-genetic variation. A growing body of evidence suggests that metabolic heterogeneity m…
q-bio.MN2019
Stochastic modelling reveals mechanisms of metabolic heterogeneity
Mona K. Tonn, Philipp Thomas, Mauricio Barahona +1
Phenotypic variation is a hallmark of cellular physiology. Metabolic heterogeneity, in particular, underpins single-cell phenomena such as microbial drug tolerance and growth varia…