87 citations · 432 across the 21 of their papers we have counts for
21 papers
Amoeboid cell migration and shape dynamics driven by actin polymerization
Winfried Schmidt, Chaouqi Misbah, Alexander Farutin
Cell migration is fundamental to development, tissue organization, immune response, and disease progression. Amoeboid motility is distinguished by rapid motion and strongly fluctua…
When Blood Parts Ways: Phase Separation in Microstructured Environments
Sampad Laha, Ananta Kumar Nayak, Alexander Farutin +2
Understanding how red blood cell (RBC) suspensions navigate porous materials is critical for for both fundamental physiology, such as maternal-fetal exchange in the placenta, and t…
Contactless indentation of a soft boundary by a rigid particle in shear flow
Alexander Farutin
The dynamics of a rigid particle above a fluid-fluid interface in shear flow is studied here numerically and analytically as a function of the downward force applied on the particl…
Towards a universal law for blood flow
Alexander Farutin, Abdessamad Nait-Ouhra, Gopal Dixit +4
Despite decades of research on blood flow, an analogue of Navier-Stokes equations that accurately describe blood flow properties has not been established yet. The reason behind thi…
A numerical framework for phoretic particles
Zhe Gou, Alexander Farutin, Chaouqi Misbah
We develop a numerical a framework to study phoretic particle dynamics in two dimensions. The particles are modeled as chemically active rigid circles, which can emit or absorb a s…
Myosin-independent amoeboid cell motility
Winfried Schmidt, Walter Zimmermann, Chaouqi Misbah +1
Mammalian cell polarization and motility are important processes involved in many physiological and pathological phenomena, such as embryonic development, wound healing, and cancer…
Singular Bifurcations : a Regularization Theory
Alexander Farutin, Chaouqi Misbah
Several nonlinear and nonequilibrium driven as well as active systems (e.g. microswimmers) show bifurcations from one state to another (for example a transition from a non motile t…
Motility and Swimming: Universal Description and Generic Trajectories
A. Farutin, M. S. Rizvi, W. F. Hu +3
Autonomous locomotion is a ubiquitous phenomenon in biology and in physics of active systems at microscopic scale. This includes prokaryotic, eukaryotic cells (crawling and swimmin…
Swirling and snaking, 3D oscillatory bifurcations of vesicle dynamics in microcirculation
Jinming Lyu, Paul G. Chen, Alexander Farutin +3
Vesicles are soft elastic bodies with distinctive mechanical properties such as bending resistance, membrane fluidity, and their strong ability to deform, mimicking some properties…
Erythrocyte-erythrocyte aggregation dynamics under shear flow
Mehdi Abbasi, Alexander Farutin, Hamid Ez-Zahraouy +2
Red blood cells (RBCs) -- erythrocytes -- suspended in plasma tend to aggregate and form rouleaux. During aggregation the first stage consists in the formation of RBC doublets [Blo…
Crawling in a fluid
Alexander Farutin, Jocelyn Etienne, Chaouqi Misbah +1
There is increasing evidence that mammalian cells not only crawl on substrates but can also swim in fluids. To elucidate the mechanisms of the onset of motility of cells in suspens…
Optimal cell transport in straight channels and networks
Alexander Farutin, Zaiyi Shen, Gael Prado +9
Flux of rigid or soft particles (such as drops, vesicles, red blood cells, etc.) in a channel is a complex function of particle concentration, which depends on the details of induc…
Predicting optimal hematocrit in silico
Alexander Farutin, Zaiyi Shen, Gael Prado +9
Optimal hematocrit maximizes oxygen transport. In healthy humans, the average hematocrit is in the range of 40-45, but it can significantly change in blood pathologie…
Blood crystal: emergent order of red blood cells under wall-confined shear flow
Zaiyi Shen, Thomas M. Fischer, Alexander Farutin +3
Driven or active suspensions can display fascinating collective behavior, where coherent motions or structures arise on a scale much larger than that of the constituent particles.…
Hydrodynamic pairing of soft particles in a confined flow
Othmane Aouane, Alexander Farutin, Marine Thiébaud +3
The mechanism of hydrodynamics-induced pairing of soft particles, namely closed bilayer membranes (vesicles, a model system for red blood cells) and drops, is studied numerically w…
Amoeboid swimming in a channel
Hao Wu, A. Farutin, W. -F. Hu +5
Several micro-organisms, such as bacteria, algae, or spermatozoa, use flagella or cilia to swim in a fluid, while many other micro-organisms instead use ample shape deformation, de…
Amoeboid motion in confined geometry
Hao Wu, M. Thiébaud, W. -F. Hu +5
Many eukaryotic cells undergo frequent shape changes (described as amoeboid motion) that enable them to move forward. We investigate the effect of confinement on a minimal model of…
Viscoelastic transient of confined Red Blood Cells
Gaël Prado, Alexander Farutin, Chaouqi Misbah +1
The unique ability of a red blood cell to flow through extremely small microcapillaries depends on the viscoelastic properties of its membrane. Here, we study in vitro the response…
Shape diagram of vesicles in Poiseuille flow
Gwennou Coupier, Alexander Farutin, Christophe Minetti +2
Soft bodies flowing in a channel often exhibit parachute-like shapes usually attributed to an increase of hydrodynamic constraint (viscous stress and/or confinement). We show that…
New analytical progress in the theory of vesicles under linear flow
Alexander Farutin, Thierry Biben, Chaouqi Misbah
Vesicles are becoming a quite popular model for the study of red blood cells (RBCs). This is a free boundary problem which is rather difficult to handle theoretically. Quantitative…
Numerical study of 3D vesicles under flow: discovery of new peculiar behaviors
Thierry Biben, Alexander Farutin, Chaouqi Misbah
The study of vesicles under flow, a model system for red blood cells (RBCs), is an essential step in understanding various intricate dynamics exhibited by RBCs in vivo and in vitro…