3 papers
q-bio.PE2026
Integrating opportunities and parametrized signatures for improved mutational processes estimation in extended sequence contexts
Ragnhild Laursen, Marta Pelizzola, Lasse Maretty +1
Mutational signatures describe the pattern of mutations over the different mutation types. Each mutation type is determined by a base substitution and the flanking nucleotides to t…
cs.LG2026
MM-algorithms for traditional and convex NMF with Tweedie and Negative Binomial cost functions and empirical evaluation
Elisabeth Sommer James, Asger Hobolth, Marta Pelizzola
Non-negative matrix factorisation (NMF) is a widely used tool for unsupervised learning and feature extraction, with applications ranging from genomics to text analysis and signal…
stat.AP2019
Modifying the Chi-square and the CMH test for population genetic inference: adapting to over-dispersion
Kerstin Spitzer, Marta Pelizzola, Andreas Futschik
Evolve and resequence studies provide a popular approach to simulate evolution in the lab and explore its genetic basis. In this context, the chi-square test, Fishers exact test, a…