6 papers
Whole Blood-Based Point-of-Care Assay for Single-Tier Lyme Disease Testing
Mihye Lee, Rajesh Ghosh, Artem Goncharov +10
Rapid point-of-care diagnostics that operate directly on whole blood can accelerate clinical decision-making by bypassing complex sample preprocessing and centralized laboratory in…
Autonomous Uncertainty Quantification for Computational Point-of-care Sensors
Artem Goncharov, Rajesh Ghosh, Hyou-Arm Joung +2
Computational point-of-care (POC) sensors enable rapid, low-cost, and accessible diagnostics in emergency, remote and resource-limited areas that lack access to centralized medical…
A paper-based multiplexed serological test to monitor immunity against SARS-CoV-2 using machine learning
Merve Eryilmaz, Artem Goncharov, Gyeo-Re Han +6
The rapid spread of SARS-CoV-2 caused the COVID-19 pandemic and accelerated vaccine development to prevent the spread of the virus and control the disease. Given the sustained high…
Deep learning-enhanced paper-based vertical flow assay for high-sensitivity troponin detection using nanoparticle amplification
Gyeo-Re Han, Artem Goncharov, Merve Eryilmaz +11
Successful integration of point-of-care testing (POCT) into clinical settings requires improved assay sensitivity and precision to match laboratory standards. Here, we show how inn…
Fluid dynamics alters liquid-liquid phase separation in confined aqueous two-phase systems
Eric W. Hester, Sean P. Carney, Vishwesh Shah +4
Liquid-liquid phase separation is key to understanding aqueous two-phase systems (ATPS) arising throughout cell biology, medical science, and the pharmaceutical industry. Controlli…
Shape-design for stabilizing micro-particles in inertial microfluidic flows
Aditya Kommajosula, Daniel Stoecklein, Dino Di Carlo +1
Design of microparticles which stabilize at the centerline of a channel flow when part of a dilute suspension is examined numerically for moderate Reynolds numbers ($10 \le Re \le…