94 citations · 205 across the 7 of their papers we have counts for
4 papers · 1 filter
Bayesian Nonparametric Estimation for Dynamic Treatment Regimes with Sequential Transition Times
Yanxun Xu, Peter Mueller, Abdus S. Wahed +1
Dynamic treatment regimes in oncology and other disease areas often can be characterized by an alternating sequence of treatments or other actions and transition times between dise…
A Latent Gaussian Process Model with Application to Monitoring Clinical Trials
Yanxun Xu, Yuan Ji
In many clinical trials treatments need to be repeatedly applied as diseases relapse frequently after remission over a long period of time (e.g., 35 weeks). Most research in statis…
Subgroup-Based Adaptive (SUBA) Designs for Multi-Arm Biomarker Trials
Yanxun Xu, Lorenzo Trippa, Peter Müller +1
Targeted therapies based on biomarker profiling are becoming a mainstream direction of cancer research and treatment. Depending on the expression of specific prognostic biomarkers,…
MAD Bayes for Tumor Heterogeneity Feature Allocation with Non-Normal Sampling
Yanxun Xu, Peter Mueller, Yuan Yuan +2
We propose small-variance asymptotic approximations for the inference of tumor heterogeneity (TH) using next-generation sequencing data. Understanding TH is an important and open r…