56 citations · 89 across the 17 of their papers we have counts for
17 papers
Timing consistency of T cell receptor activation in a stochastic model combining kinetic segregation and proofreading
Thorsten Prüstel, Martin Meier-Schellersheim
T cell receptor signaling must operate reliably under tight time constraints. While assuming quite different mechanisms, two prominent models of T cell receptor activation, kinetic…
Grid-free stochastic simulations of reaction-diffusion processes at cell-cell contacts
Thorsten Prüstel, Martin Meier-Schellersheim
Biological cells can exchange messages through soluble molecules or membrane-bound receptors. In particular in the latter case, the interaction is usually located in specific regio…
Stochastic single-particle based simulations of cellular signaling embedded into computational models of cellular morphology
Thorsten Prüstel, Martin Meier-Schellersheim
Cells exhibit a wide variety of different shapes. This diversity poses a challenge for computational approaches that attempt to shed light on the role cell geometry plays in regula…
Path integral approach to theories of diffusion-influenced reactions
Thorsten Prüstel, Martin Meier-Schellersheim
The path decomposition expansion represents the propagator of the irreversible reaction as a convolution of the first-passage, last-passage and rebinding time probability densities…
Exact propagation without analytical solutions
Thorsten Prüstel, Martin Meier-Schellersheim
We present a simulation algorithm that accurately propagates a molecule pair using large time steps without the need to invoke the full exact analytical solutions of the Smoluchows…
Quantum mechanical inspired factorization of the molecule pair propagator in theories of diffusion-influenced reactions
Thorsten Prüstel, Martin Meier-Schellersheim
Building on mathematical similarities between quantum mechanics and theories of diffusion-influenced reactions, we discuss how the propagator of a reacting molecule pair can be rep…