690 citations · 740 across the 5 of their papers we have counts for
6 papers
New views of old proteins: clarifying the enigmatic proteome
Participants in a NIH Workshop on Functional, Integrative Proteomics, : +20
All human diseases involve proteins, yet our current tools to characterize and quantify them are limited. To better elucidate proteins across space, time, and molecular composition…
MITI Minimum Information guidelines for highly multiplexed tissue images
Denis Schapiro, Clarence Yapp, Artem Sokolov +36
The imminent release of tissue atlases combining multi-channel microscopy with single cell sequencing and other omics data from normal and diseased specimens creates an urgent need…
Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging
John W. Hickey, Elizabeth K. Neumann, Andrea J. Radtke +21
Tissues and organs are composed of distinct cell types that must operate in concert to perform physiological functions. Efforts to create high-dimensional biomarker catalogs of the…
Mapping the Human Body at Cellular Resolution -- The NIH Common Fund Human BioMolecular Atlas Program
Michael P Snyder, Shin Lin, Amanda Posgai +22
Transformative technologies are enabling the construction of three dimensional (3D) maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years,…
The Human Cell Atlas White Paper
Aviv Regev, Sarah Teichmann, Orit Rozenblatt-Rosen +78
The Human Cell Atlas (HCA) will be made up of comprehensive reference maps of all human cells - the fundamental units of life - as a basis for understanding fundamental human biolo…
Joint Modeling and Registration of Cell Populations in Cohorts of High-Dimensional Flow Cytometric Data
Saumyadipta Pyne, Kui Wang, Jonathan Irish +10
In systems biomedicine, an experimenter encounters different potential sources of variation in data such as individual samples, multiple experimental conditions, and multi-variable…