A quantitative study on the role of TKI combined with Wnt/$\beta$-catenin signaling and IFN-$\alpha$ in the treatment of CML through deterministic and stochastic approaches

Sonjoy Pan, Soumyendu Raha, Siddhartha P. Chakrabarty

We propose deterministic and stochastic models for studying the pharmacokinetics of chronic myeloid leukemia (CML), upon administration of IFN-$\alpha$ (the traditional treatment for CM…