13 citations · 16 across the 8 of their papers we have counts for
4 papers · 1 filter
Communicating results in trials with multiple hypotheses or adaptive design features
Elina Asikanius, Marcel Wolbers, Mouna Akacha +8
Over time, clinical trials have increasingly incorporated complex design and analysis elements such as interim analyses, adaptations, multiple endpoints, and sophisticated multipli…
Navigating the Landscape of Hierarchical Multi-Component Strategies: GPC, DOOR, and MOST
Mickaël De Backer, Johan Verbeeck, Vivian Lanius +5
There is a growing recognition of the importance to involve patients in every stage of drug development. This shift acknowledges that patients' perspectives, experiences, and prefe…
Clustering-Based Outcome Models for Clinical Studies: A Scoping Review
Johannes Vilsmeier, Fabian Eibensteiner, Franz König +6
This review provides a systematic overview of methods that combine covariate-based clustering of observational units (patients) with outcome models for clinical studies. We disting…
Statistical Methodology Groups in the Pharmaceutical Industry
Jenny Devenport, Tobias Mielke, Mouna Akacha +10
Research and Development is the largest budget position in the pharmaceutical industry, with clinical trials being a critical, yet costly and time-consuming component to inform dec…