most citedThe signaling signature of the neurotensin type 1 receptor with endogenous ligands

72 citations · 126 across the 4 of their papers we have counts for

collaborators

4 papers

q-bio.MN2019★ 16 cited

Angiotensin II cyclic analogs as tools to investigate AT1R biased signaling mechanisms

David St-Pierre, Jérôme Cabana, Brian J. Holleran +5

G protein coupled receptors (GPCRs) produce pleiotropic effects by their capacity to engage numerous signaling pathways once activated. Functional selectivity (also called biased s…

q-bio.CB2019★ 5 cited

Label-free cell signaling pathway deconvolution of Angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIII\IV responses

Sandrine Lavenus, Élie Simard, Élie Besserer-Offroy +3

Angiotensin II (AngII) type 1 receptor (AT1R) is a G protein-coupled receptor known for its role in numerous physiological processes and its implication in many vascular diseases.…

q-bio.MN2018★ 33 cited

The hypotensive effect of activated apelin receptor is correlated with \b{eta}-arrestin recruitment

Élie Besserer-Offroy, Patrick Bérubé, Jérôme Côté +8

The apelinergic system is an important player in the regulation of both vascular tone and cardiovascular function, making this physiological system an attractive target for drug de…

q-bio.CB2018★ 72 cited

The signaling signature of the neurotensin type 1 receptor with endogenous ligands

Élie Besserer-Offroy, Rebecca L Brouillette, Sandrine Lavenus +8

The human neurotensin 1 receptor (hNTS1) is a G protein-coupled receptor involved in many physiological functions, including analgesia, hypothermia, and hypotension. To gain a bett…