154 citations · 256 across the 4 of their papers we have counts for
5 papers
Mean-field interacting multi-type birth-death processes with a view to applications in phylodynamics
William S. DeWitt, Steven N. Evans, Ella Hiesmayr +1
Multi-type birth-death processes underlie approaches for inferring evolutionary dynamics from phylogenetic trees across biological scales, ranging from deep-time species macroevolu…
Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity
Zachary Montague, Huibin Lv, Jakub Otwinowski +12
COVID-19 patients show varying severity of the disease ranging from asymptomatic to requiring intensive care. Although a number of SARS-CoV-2 specific monoclonal antibodies have be…
Estimation of cell lineage trees by maximum-likelihood phylogenetics
Jean Feng, William S DeWitt, Aaron McKenna +3
CRISPR technology has enabled large-scale cell lineage tracing for complex multicellular organisms by mutating synthetic genomic barcodes during organismal development. However, th…
Using genotype abundance to improve phylogenetic inference
William S. DeWitt, Luka Mesin, Gabriel D. Victora +2
Modern biological techniques enable very dense genetic sampling of unfolding evolutionary histories, and thus frequently sample some genotypes multiple times. This motivates strate…
Replicate immunosequencing as a robust probe of B cell repertoire diversity
William DeWitt, Paul Lindau, Thomas Snyder +3
Fundamental to quantitative characterization of the B cell receptor repertoire is clonal diversity - the number of distinct somatically recombined receptors present in the repertoi…