3 papers
stat.ME2021
A Markov Decision Process for Response-Adaptive Randomization in Clinical Trials
David Merrell, Thevaa Chandereng, Yeonhee Park
In clinical trials, response-adaptive randomization (RAR) has the appealing ability to assign more subjects to better-performing treatments based on interim results. The traditiona…
stat.AP2019
Robust Blocked Response-Adaptive Randomization Designs
Thevaa Chandereng, Rick Chappell
In most clinical trials, patients are randomized with equal probability among treatments to obtain an unbiased estimate of the treatment effect. Response-adaptive randomization (RA…
stat.AP2018
Imbalanced Randomization in Clinical Trials
Thevaa Chandereng, Xiaodan Wei, Rick Chappell
Randomization is a common technique used in clinical trials to eliminate potential bias and confounders in a patient population. Equal allocation to treatment groups is the standar…