2 papers
stat.AP2020
Use of copula to model within-study association in bivariate meta-analysis of binomial data at the aggregate level a Bayesian approach and application to surrogate endpoint evaluation
Tasos Papanikos, John R Thompson, Keith R Abrams +1
Bivariate meta-analysis provides a useful framework for combining information across related studies and has been utilised to combine evidence from clinical studies to evaluate tre…
stat.ME2019
A Bayesian hierarchical meta-analytic method for modelling surrogate relationships that vary across treatment classes using aggregate data
Tasos Papanikos, John Thompson, Keith Abrams +4
Surrogate endpoints play an important role in drug development when they can be used to measure treatment effect early compared to the final clinical outcome and to predict clinica…