5 papers
Shannon Entropy for Time-Varying Persistence of Cell Migration
Yanping Liu, Yang Jiao, Qihui Fan +7
Cell migration, which can be significantly affected by intracellular signaling pathways (ICSP) and extracellular matrix (ECM), plays a crucial role in many physiological and pathol…
Deriving Time-varying Cellular Motility Parameters via Wavelet Analysis
Yanping Liu, Yang Jiao, Guoqiang Li +6
Cell migration is an indispensable physiological and pathological process for normal tissue development and cancer metastasis, which is greatly regulated by intracellular signal pa…
Modeling Multi-Cellular Dynamics Regulated by ECM-Mediated Mechanical Communication via Active Particles with Polarized Effective Attraction
Yu Zheng, Qihui Fan, Christopher Eddy +4
Collective cell migration is crucial to many physiological and pathological processes. Recent experimental studies have indicated that the active traction forces generated by migra…
Modeling cell migration regulated by cell-ECM micromechanical coupling
Yu Zheng, Hanqing Nan, Qihui Fan +6
Cell migration in fibreous extracellular matrix (ECM) is crucial to many physiological and pathological processes such as tissue regeneration, immune response and cancer progressio…
Modeling Three-dimensional Invasive Solid Tumor Growth in Heterogeneous Microenvironment under Chemotherapy
Hang Xie, Yang Jiao, Qihui Fan +8
A systematic understanding of the evolution and growth dynamics of invasive solid tumors in response to different chemotherapy strategies is crucial for the development of individu…