activity
20182025
most citedDeep-learning-assisted detection and termination of spiral- and broken-spiral waves in mathematical models for cardiac tissue

20 citations · 25 across the 7 of their papers we have counts for

collaborators

7 papers

nlin.CD2025

Spiral defect chaos with intermittency increases mean termination time

Mahesh Kumar Mulimani, Wouter-Jan Rappel

Cardiac models are examples of excitable systems and can support stable spiral waves. For certain parameter values, however, these spiral waves can become unstable, resulting in sp…

physics.bio-ph2024

Prediction of excitable wave dynamics using machine learning

Mahesh Kumar Mulimani, Sebastian Echeverria-Alar, Michael Reiss +1

Excitable systems can exhibit a variety of dynamics with different complexity, ranging from a single, stable spiral to spiral defect chaos (SDC), during which spiral waves are cont…

physics.bio-ph2022★ 4 cited

Spiral-wave dynamics in excitable media: Insights from dynamic mode decomposition

Mahesh Kumar Mulimani, Soling Zimik, Jaya Kumar Alageshan +1

Spiral waves are ubiquitous spatiotemporal patterns that occur in various excitable systems. In cardiac tissue, the formation of these spiral waves is associated with life-threaten…

physics.bio-ph2021

An in silico study of electrophysiological parameters that affect the spiral-wave frequency in mathematical models for cardiac tissue

Mahesh Kumar Mulimani, Soling Zimik, Rahul Pandit

Spiral waves of excitation in cardiac tissue are associated with life-threatening cardiac arrhythmias. It is, therefore, important to study the electrophysiological factors that af…

physics.bio-ph2021

Arrhythmogenicity of cardiac fibrosis: fractal measures and Betti numbers

Mahesh Kumar Mulimani, Brodie A. J. Lawson, Rahul Pandit

Infarction- or ischaemia-induced cardiac fibrosis can be arrythmogenic. We use mathematcal models for diffuse fibrosis (), interstitial fibrosis (), pat…

physics.bio-ph2019★ 20 cited

Deep-learning-assisted detection and termination of spiral- and broken-spiral waves in mathematical models for cardiac tissue

Mahesh Kumar Mulimani, Jaya Kumar Alageshan, Rahul Pandit

Unbroken and broken spiral waves, in partial-differential-equation (PDE) models for cardiac tissue, are the mathematical analogs of life-threatening cardiac arrhythmias, namely, ve…

physics.bio-ph2018★ 1 cited

Comparisons of wave dynamics in Hodgkin-Huxley and Markov-state formalisms for the Sodium (Na) channel in some mathematical models for human cardiac tissue

Mahesh Kumar Mulimani, Alok Ranjan Nayak, Rahul Pandit

We compare and contrast spiral- and scroll-wave dynamics in five different mathematical models for cardiac tissue. The first is the TP06 model, due to ten Tusscher and Panfilov, wh…