4 papers
An in silico study of electrophysiological parameters that affect the spiral-wave frequency in mathematical models for cardiac tissue
Mahesh Kumar Mulimani, Soling Zimik, Rahul Pandit
Spiral waves of excitation in cardiac tissue are associated with life-threatening cardiac arrhythmias. It is, therefore, important to study the electrophysiological factors that af…
Arrhythmogenicity of cardiac fibrosis: fractal measures and Betti numbers
Mahesh Kumar Mulimani, Brodie A. J. Lawson, Rahul Pandit
Infarction- or ischaemia-induced cardiac fibrosis can be arrythmogenic. We use mathematcal models for diffuse fibrosis (), interstitial fibrosis (), pat…
Deep-learning-assisted detection and termination of spiral- and broken-spiral waves in mathematical models for cardiac tissue
Mahesh Kumar Mulimani, Jaya Kumar Alageshan, Rahul Pandit
Unbroken and broken spiral waves, in partial-differential-equation (PDE) models for cardiac tissue, are the mathematical analogs of life-threatening cardiac arrhythmias, namely, ve…
Comparisons of wave dynamics in Hodgkin-Huxley and Markov-state formalisms for the Sodium (Na) channel in some mathematical models for human cardiac tissue
Mahesh Kumar Mulimani, Alok Ranjan Nayak, Rahul Pandit
We compare and contrast spiral- and scroll-wave dynamics in five different mathematical models for cardiac tissue. The first is the TP06 model, due to ten Tusscher and Panfilov, wh…