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stat.ME2026
Adaptive clinical trials based on design-optimal e-values with automatic curtailment: An application to single-arm trials with binary data
Stef Baas, Judith ter Schure, Joost van Rosmalen
The e-value is gaining traction as a robust alternative to p-values and Bayes factors for quantifying statistical evidence. e-values are a promising method for adaptive clinical tr…
stat.ME2019
Accumulation Bias in Meta-Analysis: The Need to Consider Time in Error Control
Judith ter Schure, Peter D. Grünwald
Studies accumulate over time and meta-analyses are mainly retrospective. These two characteristics introduce dependencies between the analysis time, at which a series of studies is…