4 papers
Enhancing the performance of DNA surface-hybridization biosensors through target depletion
Stefanos K. Nomidis, Michal Szymonik, Tom Venken +2
DNA surface-hybridization biosensors utilize the selective hybridization of target sequences in solution to surface-immobilized probes. In this process, the target is usually assum…
Twist-bend coupling, twist waves and the shape of DNA loops
S. K. Nomidis, M. Caraglio, M. Laleman +3
By combining analytical and numerical calculations, we investigate the minimal-energy shape of short DNA loops of approximately base pairs (bp). We show that in these loops t…
Twist-bend coupling and the statistical mechanics of the twistable worm-like chain model of DNA: perturbation theory and beyond
Stefanos K. Nomidis, Enrico Skoruppa, Enrico Carlon +1
The simplest model of DNA mechanics describes the double helix as a continuous rod with twist and bend elasticity. Recent work has discussed the relevance of a little-studied coupl…
DNA capture into the ClyA nanopore: diffusion-limited versus reaction-limited processes
Stefanos K. Nomidis, Jef Hooyberghs, Giovanni Maglia +1
The capture and translocation of biomolecules through nanometer-scale pores are processes with a potential large number of applications, and hence they have been intensively studie…